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Penicillin Allergy Testing in the News

What's in it for me? Benefits of penicillin allergy testing

(February 10, 2017) - While penicillin allergy testing is an emerging topic for 2017, healthcare providers are finding that new—and unexpected—patient populations do not understand the importance of penicillin allergy testing. Penicillin allergies, reported in 10 percent of the population, are the most commonly documented drug allergy in the U.S. Yet nine out of 10 patients reporting a penicillin allergy are not actually allergic.

Think you're allergic to penicillin? Check again

(February 6, 2017) - Many people who think they're allergic to penicillin don't really have an allergy to this antibiotic, a pediatric expert says. And anyone who thinks they have had an allergic reaction to penicillin should undergo an allergy test to ensure they really need to avoid these important drugs, Dr. Min Lee advised. She is a pediatric allergist at UT Southwestern Medical Center at Dallas.

Penicillin allergy test determines the safety of useful antibiotic

(December 13, 2016) - Cleveland clinic doctor David Lang says about 90 percent of patients with a penicillin allergy will lose their allergy over time – and be able to take the medicine without any risk. "It’s important because if you self-report penicillin allergy, this may be a barrier to you receiving optimal care." He says it’s important to identify who can take penicillin because, in some cases, the medicine may be less costly, more effective, and pose fewer side effects than alternatives.

You're probably not allergic to penicillin, says CDC

(October 4, 2016) - The Centers for Disease Control and Prevention says you're probably not allergic to penicillin.
Approximately 10 percent of all U.S. patients report having an allergic reaction to a penicillin-class antibiotic in their past, according to the CDC, however, fewer than 1 percent of the population is truly allergic to penicillin.

Centers for Disease Control and Prevention urges patients to confirm penicillin allergy

(October 4, 2016) - The Centers for Disease Control and Prevention says you're probably not allergic to penicillin.
Approximately 10 percent of all U.S. patients report having an allergic reaction to a penicillin-class antibiotic in their past, according to the CDC, however, fewer than 1 percent of the population is truly allergic to penicillin.

Press Releases

New Study: Penicillin Testing Shown to Change Treatment Course
(Baltimore, MD and Round Rock, TX) August 17, 2016 –– A new study from the University of Maryland reveals that testing hospital patients for penicillin allergy leads to optimal antibiotic treatment, since most people who think they are allergic to penicillin are actually not.1  And finding out doesn’t take an allergist: the study evaluated a penicillin allergy skin testing program that was managed by infectious diseases physician fellows who were able to appropriately assess patients for penicillin allergy and perform the testing.   Treatment can be improved as a result of penicillin allergy testing according to the study:
  • 84% of those who tested negative for penicillin allergy were given antibiotic changes
  • 63% received a narrower spectrum antibiotic
  • 80% received more effective therapy
  • and 61% received more cost effective therapy.
  “Our study confirmed that many people who think they have a penicillin allergy actually do not when penicillin allergy testing is performed,” says Emily L. Heil, PharmD, BCPS-AQ ID, lead author of the study and an Assistant Professor of Pharmacy Practice and Science at the University of Maryland School of Pharmacy.  “This is hugely important since patients with reported penicillin allergies tend to get suboptimal antibiotic therapy compared to patients without reported penicillin allergies.”      Skin testing was conducted on 76 people who said they were allergic to penicillin while they were patients at the University of Maryland Medical Center.  Of the valid tests, 96 percent were negative (not allergic), according to the study published in July 2016 in Open Forum Infectious Diseases, a peer-reviewed journal from Oxford University Press.   Heil and colleagues, who include several researchers from the University of Maryland School of Medicine, conducted a study to assess the feasibility of a penicillin allergy skin testing service managed by physicians in the Infectious Diseases Fellowship Program.   Fellows received education and training in penicillin allergy testing, then consulted with various hospital departments to select patients for assessment and to undergo skin testing.   Training infectious diseases fellows proved to be a “great resource,” Heil says, since many allergists work only in outpatient settings and do not see patients in hospitals.  In fact, a national survey of infectious disease specialists, conducted by the University of Maryland, indicates that lack of time and inadequate personnel are the main barriers to penicillin skin testing. Yet, those surveyed note that penicillin allergy is often overstated and affects antibiotic choice, so teaching infectious disease fellows how to evaluate and test for penicillin allergy could enhance patient care and cost savings, Heil notes.   “For other institutions without access to inpatient allergist services, infectious diseases physicians can help provide this important service,” Heil notes.       For more information on the University of Maryland study visit: http://ofid.oxfordjournals.org/content/early/2016/07/22/ofid.ofw155.abstract   For more on penicillin allergy testing visit: www.prepen.com
  1. Implementation of an Infectious Disease Fellow Managed Penicillin Allergy Skin Testing Service, Open Forum Infectious Diseases July 22, 2016, http://ofid.oxfordjournals.org/content/early/2016/07/22/ofid.ofw155.abstract
  2. Antibiotic Stewardship in Acute Care: A Practical Playbook, U.S. Centers for Disease Control and Prevention (CDC), 2016.

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