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Get in touch

For more information or support, fill out the form below, or send us a tweet.

Why Penicillin Allergy Testing?

PRE-PEN® (benzylpenicilloyl polylysine injection USP) is the only FDA approved skin test for the diagnosis of penicillin allergy. Penicillin allergy testing can be performed safely on hospitalized patients and suggests improved outcomes, less vancomycin use, and potential cost savings. Penicillin skin testing is the most rapid, sensitive, and cost-effective modality for evaluating patients with immediate allergic reactions to penicillin.


Overuse of broad-spectrum antibiotics leads to development and spread of multiple drug-resistant bacteria


Having a label of antibiotic allergy can lead to the withholding of guideline recommended antimicrobial therapies 


The mean antibiotic cost for patients allergic to penicillin is 63% higher than for those not allergic to penicillin

Antimicrobial Stewardship

Penicillin allergy testing can be a safe and effective strategy to reduce the use of broad spectrum antibiotics and can help modify antibiotic selection.

Penicillin Allergy

Penicillin allergy is the most commonly reported drug allergy in the United States however only 9 out of 10 patients who report as allergic are truly allergic when skin tested, Because of this, patients often receive antibiotics that are not optimal for their condition which can result in treatment delays and increased costs.

Penicillin Skin Testing in Your Hospital

Penicillin skin testing can benefit your hospital in many clinical areas including pre-op testing, Infectious Disease, ICU, and ER as well as out-patient clinics.


In Practice: Journal of Allergy and Clinical Immunology

Penicillin skin testing is a safe and effective tool for evaluating penicillin allergy in the pediatric population.

Journal of Hospital Medicine

The impact of penicillin skin testing on clinical practice and antimicrobial stewardship.

Annals of Allergy, Asthma & Immunology

Frequency of systemic reactions to penicillin skin tests.

Contact ALK at or 1-800-325-7354 to learn how ALK can help you impact antibiotic treatment through penicillin allergy testing.